Hamilton was not 35 as of 3/4/1789 so he is out. Thomas Paine was a pamphleteer and a radical. No way. Hancock OTL only got 4 votes in the election, none from MA which went for JA, and was in declining health. Without Washington I think you are looking at three primary candidates, JA, Jay, and TJ. New England, Middle, South. And maybe a Pinckney from SC. I would expect the regions to largely stick together (but some split states) but SC could well be the wild card, either by having its own favorite son or not backing TJ. I don't recall the EV breakdown, but it seems that the big three would end up battling it out in the HoR, and with 1 vote per state and 7 needed to win, someone is going to have to deal. Not a good look for a new Republic starting out.