Yes but if Viking do arrive in 12 century and these colonizers continue with regular contact back to Europe then Columbus will not arrive in 1492 because Europe will hear about America’s existence. If they arrive and become cutoff then they too will become victims of the diseases starting in 1492. Remember science shows us that the diseases in 15-16th century were different than those in the 12 century.
One more thing the Vikings have provided the natives no immunity plus they have introduced the disease much earlier and affected the natives in similar fashion. So the natives populations will be lower and weaker when Europeans arrive again in 1492.
In this context immunity is provided by a population having contact with the disease, it just it tales time and a lot of people die in the meantime (depending on how it's introduced and other exacerbating or mitigating factors))
The thing is the C16th colonisation was faster than a C12th century colonisation would be, on top of that the technological disparity was greater as was European population sizes and resources and capability to drive it. Meaning that once they got there colonisation flowed faster in greater numbers and with greater ability to "finish the job" with other interactions. Another way this expresses is once CC comes back the word of his discovery quickly spreads throughout Europe, and there were several nations and organisations who could kick start colonisation (despite attempts by some to control access). This is partly because of the increased population and resources as mentioned above but also because Europe is much more "joined up" place in the C16th than it is the C12th.
Then there's where the different colonisers went. the Viking landed in the north east a relatively underpopulated and isolated part of the continent. If they had stayed or even slowly moved down and in, even if they were interacting with locals there the sheer distances and isolation of that ares would have decelerated the spread of diseases into the whole continent. C16th colonisation on the other hand landed right in heavily populated areas of the continent with established vectors of communications thus speeding up the process
Then there's also the point that C12th viking are in terms of resources and technology on much more equal terms with the people they'll meet in terms of being able to subjugate them even in a weakened state. The follow up subjugation is important not just in terms of physically doing it additionally stress an already disease stressed population but the quicker settlers move in the faster they can spread additional diseases that will effect an already weakened population.
Basically anything that can slow colonisation down in terms of numbers of interactions between new populations and how quickly they mingle will buy more time for the native population to absorb and then recover in the face of it.
Ultimately you are right once discovered by Europeans and that gets established NA is going to never be undiscovered so there will be colonisation and thus interaction, but it's how it happens that's key here.
I'm no expert... if the Vikings could make it to Greenland back and forth (until the Little Ice Age struck), what did they have what the Carthaginians didn't have? - If an antique people could make it, I guess it'd be them.
They Island hopped, which brings up the point above regarding the different nature of the colonisation. The Viking led colonisation of NA would have to be a more multi stage process than the later C16th colonisation. I.e you are going to have to have staging points at teh very least in Iceland and Greenland, all of which adds friction to the process (and it would also allow those lands to control it more tightly)
Ok but 200 years the measles will and did mutate and just like Spanish flu hit right after WWI if it hit today it would still kill tens of millions so we did not become immune to it and people 100 or 200 years would not be imune to the mutated disease.
It can do certainly, but it's not guaranteed too and regular strains still say around. And since mutated species are seldom completely new pre-existing population experience with other strains helps. As a point of comparison Spanish flu it actually only had a mortality rate (including 2ndary infections) of 2.5%! (only is a relative term) what made it so bad was how quickly in spread having infected an estimated 30% of the world population by 1919.