DBWI: Jack the Ripper choses different targets

This is something I've always wondered: would it change anything, if Jack the Ripper had chosen different targets? If he had killed commoners instead of nobles? Or even if he hadn't killed the Queen?
[ PLEASE nobody trot out the stupid conspiracy theory that King Eddy was the real Ripper and butchered his grandma + dad to steal the throne -- he wasn't even in London at the time, and frankly wouldn't have the nerve or the brains to do such a thing ]