Come on guys, Axis victories of pretty wanktastic proportions are not only an AH standard but quite common to this very board.
Why, a favorite for some and dreaded cliche for others is Rommel getting the tanks he needs to push through the British in Egypt and take the Middle-East, thus fueling the Axis war machine and allowing the Germans to invade Russia from West and South simultaneously, perhaps catching Stalin in Moscow with his pants down before men and material can be evacuated to Eastward (thus preventing the Ruskies from being able to withdraw and let the Russian Winter kill the Nazis for them).
With German/Italy having knocked out the Soviet Union for all intents and purposes, gorged themselves on the world's oil reserves, and put themselves in the position of making the Mediterranean an Axis lake, things look grim for Britain and the U.S. has not joined the war yet (with the gleeful Japanese seizing Soviet Vladivostok and inspiring native troops to mutiny in India, rather than turning to Pearl Harbor).
With the wave of Axis victories, Latin America goes fascist in a big way. Vargas stops playing coy and Integralist Brazil pipes up alongside Argentina in support of Germany, Peru and Chile look to Japan and the Columbians want any help they can get taking the Panama canal. A Sinarquista revolt in Mexico gives the U.S. the opportunity to enter the show, though.
While the Yanks are mopping up from Veracruz to Buenos Ares, the Brits sue for peace with the Germans in order to focus on the Pacific, only for the British fleet and far too many brave Aussies to lose their lives against the Japanese (with stiff support from the new Indian Republic). The failure to liberate Southeast Asia and the fall of Hong Kong, after the humiliation of making peace with Germany, causes an isolationist phase; with Australia, no longer confident that the Commonwealth can protect it, becoming a fortress unto itself unwilling to risk its longterm survival on further ventures.
By the time the US has shown itself to be a global superpower like no other by finishing up in the Americas, the Germans have puppet states going in Iran and N. India and the Latin Fascists (French State, Fascist Italy, Franco's Spain) have taken Free French West Africa and consolidated North Africa. Most disturbingly, in that time the Union of Fascists took over Britain in order to make it a "equal in the New World Order" rather than the sick man of Europe, with similar occurrences in apartheid South Africa and in Yellow Peril obsessed (though not without reason) Fortress Australasia.
The Americas (with the British royals having moved to Canada) and the German-backed Fascist sphere are nuclear superpowers, with the Americas outproducing and outpacing in terms of research the Fascists by quite a lot.
The Greater East Asian Co-Prosperity Sphere is cracking, with the Japanese-backed southern India Republic disintegrating in it's increasingly Hindu Fascist anti-muslim bent, with sympathetic Islamic revolts in Indonesia taxing Japanese manpower. With Indian troops being recalled to fight the Bangladeshi separatists, Southeast Asian Sphere "members" are getting nationalist ideas. And the Sphere was never able to get beyond the coast into Nationalist South China, much less crack the rump-Soviet/Chinese-communist "Eurasian Soviets" nut.
Simply put, the Co-Prosperity Sphere is up for grabs - the question is whether the German Bloc or the US Bloc will get their first. A limited nuclear strike could decapitate what capabilities in that area the Sphere has, the only thing lacking until this point has been the political will. As soon as the Sphere became fragile enough that mass invasion seemed like a good prospect, the worldwide nuclear standoff made it seem like a very bad idea. But now the Americans (and their allies) and Germans (and their allies) are getting antsy, and both sides are considering it well worth the potential risk to swoop into East Asia.
The question is, will it be German missiles from North India ("Hindustan") and Iran, or those new interhemispheric missiles from the American Bloc?
LOL. 